Publikationen am BMWZ
2026
Kagho, M. D., Schmidt, K., Chakrabarti, A., Karger, M., Lambert, C., Hauser, M., Cox, R. J., Rottner, K., Stadler, M., Stradal, T. E., & Klahn, P. (2026). Exploring the Substitution of the C21-OAc Moiety in [11]Cytochalasans: Synthesis and Evaluation of Fluorophore Conjugates. CHEMBIOCHEM, 27(1), Artikel e202500794. https://doi.org/10.1002/cbic.202500794
2025
Akula, R. K., El Kilani, H., Metzen, A., Röske, J., Zhang, K., Göhl, M., Arisetti, N., Marsh, G. P., Maple, H. J., Cooper, M. S., Karadogan, B., Jochmans, D., Neyts, J., Rox, K., Hilgenfeld, R., & Brönstrup, M. (2025). Structure-Based Optimization of Pyridone α-Ketoamides as Inhibitors of the SARS-CoV-2 Main Protease. Journal of medicinal chemistry, 68(3), 2920–2941. https://doi.org/10.1021/acs.jmedchem.4c02172
Beutling, U., Hotop, S. K., Frank, R., & Brönstrup, M. (2025). Facile High-Throughput Pre-purification of Biological Samples for Library-Scale Peptide Interaction Studies. In Methods in Molecular Biology (S. 181-187). (Methods in Molecular Biology; Band 2934). Humana Press Inc.. https://doi.org/10.1007/978-1-0716-4578-9_13
Boudrioua, A., Joiner, J. D., Grin, I., Kronenberger, T., Korotkov, V. S., Steinchen, W., Kohler, A., Schminke, S., Schulte, J. C., Pietsch, M., Naini, A., Kalverkamp, S., Hotop, S. K., Coyle, T., Piselli, C., Coles, M., Rox, K., Marschal, M., Bange, G., ... Wagner, S. (2025). Discovery of synthetic small molecules targeting the central regulator of Salmonella pathogenicity. Science advances, 11(15), Artikel eadr5235. https://doi.org/10.1126/sciadv.adr5235
Brvar, M., O’Neill, T. J., Plettenburg, O., & Krappmann, D. (2025). An updated patent review of MALT1 inhibitors (2021–present). Expert Opinion on Therapeutic Patents, 35(6), 639-656. https://doi.org/10.1080/13543776.2025.2484371
Bui, V. H., Nguyen, T. A. M., Kim, T., Liu, S., Seligmann, B., Daneshgar, P., Nguyen, T. D., Zandberg, W. F., Franke, J., & Dang, T. T. T. (2025). Discovery of corynanthe synthases in Camptotheca acuminata: medium-chain dehydrogenase/reductase-based gateway to corynanthe-type compound diversification. PLANTA, 262(4), Artikel 80. https://doi.org/10.1007/s00425-025-04792-0
Ewert, W., Bartens, C., Ongouta, J., Holmes, M., Heutling, A., Kishore, A., Urbansky, T., Zeilinger, C., Preller, M., & Kirschning, A. (2025). Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus. Nature Communications, 16(1), Artikel 2464. https://doi.org/10.1038/s41467-025-57013-3
Hakim, S. E., Liu, S., Herzog, R., Arafa, A., de Vries, J., Dräger, G., & Franke, J. (2025). Expansion of the Stereochemical Space of Triterpenes by Mining Noncanonical Oxidosqualene Cyclases Across the Diversity of Green Plants. Journal of the American Chemical Society, 147(12), 10320-10330. https://doi.org/10.1021/jacs.4c16956
Hakim, S. E., Choudhary, N., Malhotra, K., Peng, J., Bültemeier, A., Arafa, A., Friedhoff, R., Bauer, M., Eikenberg, J., Witte, C. P., Herde, M., Heretsch, P., Pucker, B., & Franke, J. (2025). Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis. Nature Communications, 16(1), Artikel 6367. https://doi.org/10.1038/s41467-025-61686-1
Hauser, M., Schmidt, K., Beiderwieden, L., Yi, C., Gerdes, K., Kalesse, M., Gerke, J., Stradal, T. E., & Cox, R. J. (2025). Synthesis of l-β-(6-azulenyl)alanine and the fluorescent actin disruptor (6-azuleno)chalasin H. RSC Advances, 15(32), 26048-26051. https://doi.org/10.1039/d5ra04702a