Publications at the BMWZ
Showing results 1 - 10 out of 306
2025
Akula, R. K., El Kilani, H., Metzen, A., Röske, J., Zhang, K., Göhl, M., Arisetti, N., Marsh, G. P., Maple, H. J., Cooper, M. S., Karadogan, B., Jochmans, D., Neyts, J., Rox, K., Hilgenfeld, R., & Brönstrup, M. (2025). Structure-Based Optimization of Pyridone α-Ketoamides as Inhibitors of the SARS-CoV-2 Main Protease. Journal of medicinal chemistry, 68(3), 2920–2941. https://doi.org/10.1021/acs.jmedchem.4c02172
Beutling, U., Hotop, S. K., Frank, R., & Brönstrup, M. (2025). Facile High-Throughput Pre-purification of Biological Samples for Library-Scale Peptide Interaction Studies. In Methods in Molecular Biology (pp. 181-187). (Methods in Molecular Biology; Vol. 2934). Humana Press Inc.. https://doi.org/10.1007/978-1-0716-4578-9_13
Boudrioua, A., Joiner, J. D., Grin, I., Kronenberger, T., Korotkov, V. S., Steinchen, W., Kohler, A., Schminke, S., Schulte, J. C., Pietsch, M., Naini, A., Kalverkamp, S., Hotop, S. K., Coyle, T., Piselli, C., Coles, M., Rox, K., Marschal, M., Bange, G., ... Wagner, S. (2025). Discovery of synthetic small molecules targeting the central regulator of Salmonella pathogenicity. Science advances, 11(15), Article eadr5235. https://doi.org/10.1126/sciadv.adr5235
Brvar, M., O’Neill, T. J., Plettenburg, O., & Krappmann, D. (2025). An updated patent review of MALT1 inhibitors (2021–present). Expert Opinion on Therapeutic Patents, 35(6), 639-656. https://doi.org/10.1080/13543776.2025.2484371
Bui, V. H., Nguyen, T. A. M., Kim, T., Liu, S., Seligmann, B., Daneshgar, P., Nguyen, T. D., Zandberg, W. F., Franke, J., & Dang, T. T. T. (2025). Discovery of corynanthe synthases in Camptotheca acuminata: medium-chain dehydrogenase/reductase-based gateway to corynanthe-type compound diversification. PLANTA, 262(4), Article 80. https://doi.org/10.1007/s00425-025-04792-0
Ewert, W., Bartens, C., Ongouta, J., Holmes, M., Heutling, A., Kishore, A., Urbansky, T., Zeilinger, C., Preller, M., & Kirschning, A. (2025). Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus. Nature Communications, 16(1), Article 2464. https://doi.org/10.1038/s41467-025-57013-3
Hakim, S. E., Liu, S., Herzog, R., Arafa, A., de Vries, J., Dräger, G., & Franke, J. (2025). Expansion of the Stereochemical Space of Triterpenes by Mining Noncanonical Oxidosqualene Cyclases Across the Diversity of Green Plants. Journal of the American Chemical Society, 147(12), 10320-10330. https://doi.org/10.1021/jacs.4c16956
Hakim, S. E., Choudhary, N., Malhotra, K., Peng, J., Bültemeier, A., Arafa, A., Friedhoff, R., Bauer, M., Eikenberg, J., Witte, C. P., Herde, M., Heretsch, P., Pucker, B., & Franke, J. (2025). Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis. Nature Communications, 16(1), Article 6367. https://doi.org/10.1038/s41467-025-61686-1
Hauser, M., Schmidt, K., Beiderwieden, L., Yi, C., Gerdes, K., Kalesse, M., Gerke, J., Stradal, T. E., & Cox, R. J. (2025). Synthesis of l-β-(6-azulenyl)alanine and the fluorescent actin disruptor (6-azuleno)chalasin H. RSC Advances, 15(32), 26048-26051. https://doi.org/10.1039/d5ra04702a
Heimann, D., Kohnhäuser, D., Kohnhäuser, A. J., & Brönstrup, M. (2025). Antibacterials with Novel Chemical Scaffolds in Clinical Development. DRUGS, 85, 293–323. Article 115484. https://doi.org/10.1007/s40265-024-02137-x
Showing results 1 - 10 out of 306
